Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11092)
Related Products (11092)
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Etravirine-d8
0 ImagesCat. No.: HY-132508SCAS No.: 1142096-06-7Etravirine-d8 is the deuterium labeled Etravirine. Etravirine (R165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
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Oxytetracycline-13C,d3 hydrochloride
0 ImagesCat. No.: HY-W755036Oxytetracycline-13C,d3 hydrochloride is the 13C- and deuterium labeled Oxytetracycline hydrochloride (HY-B0275A). Oxytetracycline hydrochloride is an antibiotic that exhibits board-spectrum antibacterial activity. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity.
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Domperidone-13C6
0 ImagesCat. No.: HY-B0411S2Synonyms: R33812-13C6Domperidone-13C6 (R33812-13C6) is 13C labeled Domperidone. Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine.
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Vildagliptin-d6
0 ImagesCat. No.: HY-14291S5Synonyms: LAF237-d6 ; NVP-LAF 237-d6Vildagliptin-d6 (LAF237-d6 ) is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity.
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D-(+)-Cellobiose-13C
0 ImagesCat. No.: HY-N2325SCAS No.: 2460737-42-0D-(+)-Cellobiose-13C is the 13C labeled D-(+)-Cellobiose. D-(+)-Cellobiose is an endogenous metabolite.
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C18:0 GM1 Ganglioside-d5 ammonium
0 ImagesC18:0 GM1 Ganglioside-d5 (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).
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Mavatrep-d6
0 ImagesCat. No.: HY-16935SSynonyms: JNJ-39439335-d6Mavatrep-d6 (JNJ-39439335-d6) is a deuterated labeled Mavatrep (HY-16935). Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (Ki=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca2+ influx with an IC50 value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain.
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3,3′-Dichloro biphenyl-13C12
0 ImagesCat. No.: HY-W718472S3,3′-Dichloro biphenyl-13C12 is 13C labeled 3,3'-Dichloro-1,1'-biphenyl.
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Seliciclib Carboxylic Acid-d7
0 ImagesCat. No.: HY-157071SCAS No.: 849108-26-5Seliciclib Carboxylic Acid-d7 is deuterium-labeled Seliciclib Carboxylic Acid.
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(Rac)-DPPC-d6
0 ImagesCat. No.: HY-109506S2CAS No.: 82765-17-1Synonyms: (Rac)-129Y83-d6(Rac)-DPPC-d6 is a deuterated labeled DPPC. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
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Tofersen-d27
0 ImagesCat. No.: HY-132580SSynonyms: BIIB067-d27; ISIS-SOD1Rx-d27; ISIS 333611-d27Tofersen-d27 (BIIB067-d27) is the deuterium labeled Tofersen (HY-132580). Tofersen (BIIB067) is an antisense oligonucleotide and SOD1 mRNA inhibitor with an IC50 of 320 pM. Tofersen mediates RNase H-dependent degradation of SOD1 mRNA to reduce SOD1 protein levels in cerebrospinal fluid and serum. Tofersen downregulates cerebrospinal fluid neurofilament light chain, neurofilament heavy chain, amyloid-beta 1-40, amyloid-beta 1-42, neuropeptide Y, ubiquitin C-terminal hydrolase L1, neuropentraxins 1, 2, R, corticotropin-releasing hormone, IL-15, and serum neurofilament light chain, neurofilament heavy chain. Tofersen can be used for the research of superoxide dismutase 1-associated amyotrophic lateral sclerosis.
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2-Fluoro-1,3-bis(methyl)benzene-d6
0 ImagesCat. No.: HY-W012808SCAS No.: 2913220-03-62-Fluoro-1,3-bis(methyl)benzene-d6 is the deuterium labeled 2-Fluoro-1,3-dimethylbenzene (HY-W012808).
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3-O-Acetyltylosin-d3
0 ImagesCat. No.: HY-W585906S3-O-Acetyltylosin-d3 is a deuterated labeled 3-O-Acetyltylosin.
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DMT-dT Phosphoramidite-13C10,15N2
0 ImagesCat. No.: HY-W013068SCAS No.: 2483830-17-5DMT-dT Phosphoramidite-13C10,15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite. DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
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Glycidyl Stearate-CC3
0 ImagesCat. No.: HY-W747639CAS No.: 2725395-41-3Glycidyl Stearate-13C3 is 13C labeled Glycidyl stearate. Oxiran-2-ylmethyl stearate is a compound belonging to the class of esters. It contains reactive oxirane or epoxy groups that give the molecule its unique properties. Oxiran-2-ylmethyl stearate is derived from stearic acid and epichlorohydrin, which are naturally occurring substances. Glycidyl stearate is commonly used in various industrial applications such as the production of coatings, adhesives and surfactants. It can also be used as a crosslinking agent in the manufacture of polymers and resins.
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Tamsulosin-d4
0 ImagesCat. No.: HY-B0661SCAS No.: 1231943-97-7Synonyms: (R)-(-)-YM12617 free base-d4; LY253351 free base-d4Tamsulosin-d4 ((R)-(-)-YM12617 (free base)-d4) is deuterium labeled Tamsulosin. Tamsulosin ((R)-(-)-YM12617 free base) is an inhibitor of α1-adrenergic receptor. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth in animal models.
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2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)-13C2,15N2
0 ImagesCat. No.: HY-165696S2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)-13C2,15N2 is 13C and 15N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium).
